Instructor

Dr. Fairchild, also known as "The Instructor", will run you through the basics of the game mechanics. He is a reliable source of Bone Meal as you work to figure out how to push back the blight (which will eventually allow spawning of traditional enemies). He also helps point out some of the features that can make life on Blightfall easier.

Starting Quests
Unlocked from the very beginning, you will need to complete these quests before you can access some of the other questlines.

Optional Tutorial
These quests are unlocked by completing "Tutorials, please!"

The following quests are unlocked by ??? (Smeltery Questline)

Teching Up Quests
This quest can be completed a couple of ways, but it's basic goal is to help you tech up to Diamond-level mining (necessary for Enchanting, Botania, Applied Energistics, and eventually Thaumcraft.

Misc. Quests
This includes both the food-related quests which guide you through making a Cooking Table, as well as a small quest meant to point out the presence of Bibliocraft.